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Quick verdict
A well-built hydrating ampoule with niacinamide, licorice extract and hyaluronic acid alongside its PDRN, carrying a brand name earned by a procedure you cannot buy in a bottle. Judge it on the supporting formula, which is genuinely good, and treat the clinic association as branding. If you are buying it because you read about the injectable, you are buying the wrong thing.
The REJURAN Turnover Ampoule arrives with something almost no skincare product has: a brand name people already associate with a clinic.
That association is doing an enormous amount of work, and it is worth separating what the brand earned from what the bottle can deliver.
Where the name comes from
REJURAN built its reputation on an injectable — a treatment administered by a practitioner, delivered underneath the skin barrier rather than onto it.
That distinction is the entire story. An injection puts the material where the cells are. A serum puts it on a surface specifically evolved to keep large molecules out. We went through this at length with PDRN generally, and the same physics applies regardless of how good the brand’s clinic reputation is.
So the honest framing: you can buy the brand. You cannot buy the procedure.
What c-PDRN means
The ampoule is built around what REJURAN calls c-PDRN — their own trademarked form of the ingredient.
A trademark tells you the brand has a proprietary version and standardises it in-house. That is a real thing and better than a generic listing. What it is not is independent evidence that the topical form does anything. Those are separate claims and only one of them is backed.
Treat a trademarked ingredient the way you would treat any branded ingredient name: it tells you about the supply chain, not about the outcome.
What is actually in the REJURAN Turnover Ampoule
Here is where the product earns a genuine recommendation, and it has nothing to do with the headline.
Alongside the PDRN, the ampoule contains niacinamide, licorice extract and hyaluronic acid. Those three have no evidence problem at all:
- Niacinamide — barrier support, sebum balance, gradual work on uneven tone. Well studied, well tolerated.
- Licorice extract — a long-established brightening ingredient, gentle enough for daily use.
- Hyaluronic acid — hydration, with the usual requirement that you seal it.
That is a coherent brightening-and-hydrating serum. If it were sold under a name nobody recognised, it would still be a reasonable purchase — just at a different price.
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What to expect, and when
Reviews of this category describe hydration and smoother texture within a week or two, and firmness or brightness at the four-week mark.
The first part is plausible and unremarkable — that is what humectants and niacinamide do. The second is where expectation management matters. Skin looking better hydrated reads as firmer, and that is a real visible effect rather than a structural change. Nothing applied to the surface rebuilds collagen in four weeks.
Judge it at eight weeks, on comfort and tone rather than on renewal.
Sizes and sets
The standard size of the REJURAN Turnover Ampoule is the sensible way to test whether your skin likes it. Larger bottles make sense once you know, and bundles pairing the ampoule with a cream solve the sealing problem the ampoule creates — there is nothing occlusive in it, so it needs something over the top regardless.
Check the current price on Amazon
Check the current price on Amazon
Who this suits
Anyone wanting a gentle brightening serum. Niacinamide plus licorice is a sensible, low-risk combination and this delivers it comfortably.
Sensitive skin. No acids, no retinoids, nothing that requires an adjustment period.
People already using the injectable. As at-home maintenance between appointments this makes sense — provided you understand it is maintenance of your routine, not of the treatment.
Who should skip it
Anyone buying it for the clinic association. That is the part that does not transfer, and it is the most expensive part of what you are paying for.
Anyone wanting firmness results. Retinoids have far more behind them, and peptides more than PDRN does topically.
Anyone with a compromised barrier. A serum is not the fix. Repair first, then add treatments.
FAQ
Is this the same as the REJURAN injection?
No. The injectable is a clinical procedure delivered below the skin barrier. The ampoule sits on top of it. They share a brand and an ingredient family, not a mechanism.
Does topical PDRN work?
The evidence for topical use is thin. The research behind PDRN concerns injected forms. Buy the ampoule for the niacinamide, licorice and hydration, all of which are well supported.
How many drops?
Three or four for the whole face, pressed rather than rubbed. More is not absorbed faster — it just runs off.
Can I use it with retinol?
Yes. There is nothing in it that conflicts, and niacinamide supports the barrier during the retinoid adjustment period.
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The bottom line
The REJURAN Turnover Ampoule is a good hydrating and brightening serum sold on the reputation of a procedure it cannot replicate.
Buy it because niacinamide, licorice and hyaluronic acid in a comfortable base is a sound routine addition. Do not buy it because you read about the injectable — that is the one thing in the bottle that is not actually in the bottle.